TOP 20 DEADLIEST LARGE-LOSS FIRES IN THE UNITED STATES (1)
| Rank | Date | Event | Location | Fatalities |
|---|---|---|---|---|
| 1 | Sep. 11, 2001 | The World Trade Center | New York, NY | 2,666 |
| 2 | Dec. 30, 1903 | Iroquois Theatre | Chicago, IL | 602 |
| 3 | Nov. 28, 1942 | Cocoanut Grove night club | Boston, MA | 492 |
| 4 | Apr. 21, 1930 | Ohio State Penitentiary | Columbus, OH | 320 |
| 5 | Mar. 18, 1937 | Consolidated School gas explosion | New London, TX | 294 |
| 6 | Dec. 5, 1876 | Conway's Theatre | Brooklyn, NY | 285 |
| 7 | Apr. 23, 1940 | Rhythm Club | Natchez, MS | 207 |
| 8 | Mar. 4, 1908 | Lakeview Grammar School | Collinwood, OH | 175 |
| 9 | Jan. 12, 1908 | Rhodes Opera House | Boyertown, PA | 170 |
| 10 | Jul. 6, 1944 | Ringling Brothers Barnum & Bailey Circus | Hartford, CT | 168 |
| 10 | Apr. 19, 1995 | Alfred P. Murrah Federal Building | Oklahoma City, OK | 168 |
| 12 | May 28, 1977 | Beverly Hills Supper Club | Southgate, KY | 165 |
| 13 | Mar. 25, 1911 | Triangle Shirtwaist Company | New York, NY | 146 |
| 14 | Apr. 10, 1917 | Eddystone Ammunition Company plant explosion | Eddystone, PA | 133 |
| 15 | May 15, 1929 | Cleveland Clinic Hospital | Cleveland, OH | 125 |
| 16 | Dec. 7, 1946 | Winecoff Hotel | Atlanta, GA | 119 |
| 17 | Feb. 20, 2003 | The Station Nightclub | W. Warwick, RI | 100 |
| 18 | Dec. 1, 1958 | Our Lady of the Angels School | Chicago, IL | 95 |
| 19 | Mar. 25, 1990 | Happy Land Social Club | New York, NY | 87 |
| 20 | Nov. 21, 1980 | MGM Grand Hotel | Las Vegas, NV | 85 |
(1) Based on deadliest single-builiding or complex fires and explosions.
Source: National Fire Protection Association.